Is Buprenorphine Used For Alcohol Addiction?

Robert Gerchalk

Robert is our health care professional reviewer of this website. He worked for many years in mental health and substance abuse facilities in Florida, as well as in home health (medical and psychiatric), and took care of people with medical and addictions problems at The Johns Hopkins Hospital in Baltimore. He has a nursing and business/technology degrees from The Johns Hopkins University.

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Understanding Buprenorphine’s Role in Alcohol Withdrawal: A Comprehensive Guide

Alcohol withdrawal is the physical and mental response to sudden cessation of alcohol intake. While it is needed to stop alcohol dependence, this process can cause physical and psychological symptoms. Buprenorphine is now being considered for its potential in managing alcohol withdrawal symptoms. This medication is one way to get relief for those going through this process. Here is what you need to know about buprenorphine and alcohol withdrawal. 

What Happens During the Alcohol Withdrawal Process?

When a person is going through alcohol withdrawal, the process can happen over a few days or even weeks. There are several stages of the process. They include:

Initial Stage (6-24 hours)

Mild symptoms like anxiety, insomnia, irritability, and increased heart rate characterize this stage. These symptoms may be the first signs that the body is adjusting to the absence of alcohol.

Intermediate Stage (24-72 hours)

During the withdrawal stage, the symptoms start to intensify. Tremors, sweating, nausea, and elevated blood pressure are some physical symptoms. Some individuals may also experience psychological symptoms like anxiety and mood disturbances.

Severe Stage (72+ hours)

Withdrawal can be a serious issue, especially for those who have a history of heavy and prolonged alcohol use. In some cases, it can lead to severe symptoms, including a potentially life-threatening condition called delirium tremens (DT). DT is characterized by hallucinations, extreme confusion, and autonomic hyperactivity.

During these times, a patient can experience discomfort. Alcohol withdrawal can cause a range of physical and psychological symptoms that vary in intensity. People may experience physical symptoms, such as tremors in their hands. Excessive sweating can lead to dehydration, and they may feel nauseous and even vomit. Their heart rate may also increase, known as tachycardia, due to the lack of alcohol in their system.

On the psychological side, individuals may feel uneasy and anxious. Along with that, there may be a sense of sadness that lingers. Mood swings can also be a part of the withdrawal experience. These symptoms can be challenging to manage during the alcohol withdrawal phase.

The severity and duration of withdrawal symptoms can vary widely among individuals. For that reason, personalized treatment plans are critical during this recovery phase.

How Buprenorphine Works

Buprenorphine is a partial opioid agonist. This medication is used for managing withdrawal symptoms and cravings associated with substance use disorders. Unlike full agonists, buprenorphine does have a ceiling effect, which means its effects plateau at a certain dose. As a result, it can reduce the risk of respiratory depression and overdose. The drug binds to opioid receptors in the brain.

Buprenorphine functions by easing the symptoms of alcohol withdrawal through its interaction with opioid receptors in the brain, a process that mimics the effects of alcohol but in a more regulated manner. This action primarily helps in lessening the physical and psychological discomfort commonly associated with withdrawal from alcohol. 

While it’s known for reducing the euphoric effects of full opioid agonists, in the context of alcohol withdrawal, its role is focused more on symptom management rather than diminishing alcohol’s euphoric effects. The strong and enduring binding of buprenorphine to these receptors not only stabilizes the brain’s chemistry during the withdrawal phase but also curtails cravings, indirectly aiding in relapse prevention. Its slow dissociation from these receptors results in a prolonged duration of action, thereby reducing the frequency of dosing compared to other withdrawal management medications.

Can Buprenorphine Help With Alcohol Withdrawals?

Buprenorphine is an effective medication for managing alcohol withdrawal symptoms. The medication’s partial agonist activity helps to reduce the intensity of withdrawal symptoms without causing sedation and respiratory depression.

This drug reduces tremors, sweating, nausea, and rapid heart rate. Along with that, it can manage psychological symptoms, such as anxiety, depression, and mood swings. Buprenorphine can stabilize a person’s emotional state, making the journey toward sobriety more comfortable. Not only does buprenorphine improve the comfort of individuals undergoing detoxification, but it also increases the likelihood of successful completion of recovery.

What Other Medications Can Treat Alcohol Withdrawal Symptoms?

Along with buprenorphine, other drugs on the market can help with alcohol withdrawal symptoms. These symptoms have traditionally been treated using benzodiazepines, such as diazepam and lorazepam. However, buprenorphine is a safer alternative due to its partial agonism and ceiling effect. 

Another medication used in the treatment of alcohol use disorder is naltrexone, an opioid receptor antagonist. However, buprenorphine has a longer duration of action, which can provide a more effective method for managing cravings and withdrawal symptoms.

Side Effects of Buprenorphine

While buprenorphine is effective in managing alcohol withdrawal and opioid use disorders, there is a potential for side effects. Common side effects associated with buprenorphine use include:

  • Nausea
  • Constipation
  • Headache
  • Insomnia

While these side effects are generally mild, they can affect the overall well-being of individuals undergoing treatment. Along with that, there have been some concerns raised regarding the potential for respiratory depression. These risks are low compared to full opioid agonists.

Additionally, there could be risks associated with using buprenorphine in combination with other central nervous system depressants. Plus, there is a possibility of misuse of buprenorphine. With careful monitoring and administration by healthcare providers, buprenorphine can be used safely and effectively to treat alcohol withdrawal.

Other Concerns With Buprenorphine Usage

Buprenorphine’s accessibility and availability remain a roadblock to helping people find a bit of relief. Geographical disparities, limited healthcare resources, and varying regulations are a few obstacles that hamper this medication’s availability. The shortage of healthcare providers authorized to prescribe buprenorphine in some regions, especially in rural or underserved areas, also limits its accessibility.

Also, financial considerations can affect the accessibility of buprenorphine. The cost of the medication and potential expenses related to medical visits and counseling may present a barrier for individuals without adequate insurance coverage or financial resources.

Medication-assisted treatment (MAT) is a type of treatment for substance use disorders that involves the use of medication with counseling and behavioral therapies. However, there is a stigma attached to MAT. Some people believe that it is just another substance substitute for alcohol or drugs.

This perception is not accurate. MAT has been proven to be effective in reducing substance abuse and improving the quality of life for individuals with addictions. Additionally, there is a fear that people can become addicted to the medication used in MAT. However, a healthcare professional carefully prescribes and monitors the drug to avoid these situations. By dispelling myths and misinformation surrounding these treatments, the medical community can encourage individuals to seek out the most effective and evidence-based options to help with alcohol withdrawal.

Can Buprenorphine Help With Mental Health Issues?

Many individuals who struggle with alcohol use disorder also face concurrent mental health conditions, ranging from anxiety and depression to more severe disorders like bipolar disorder or schizophrenia. Buprenorphine can be used to address these co-occurring disorders as well.

During alcohol withdrawal, mental health symptom exacerbation is common. Anxiety and depression can intensify as the body adjusts to the absence of alcohol. For those with pre-existing mental health conditions, withdrawal can complicate their well-being. Also, the emotional toll of withdrawal may contribute to increased vulnerability to mental health relapses.

Buprenorphine is a promising solution for tackling both substance use and mental health concerns. With its pharmacological properties, this medication is a versatile option for dual-diagnosis scenarios. Buprenorphine can help manage co-occurring disorders in two ways. First, by alleviating withdrawal symptoms associated with alcohol use, buprenorphine provides a better environment for individuals to engage in mental health help. This medication reduces physical and psychological distress, making it easier to address underlying mental health conditions.

Second, buprenorphine’s partial agonist at opioid receptors could be beneficial in regulating mood. Opioid receptors are linked to the brain’s reward and mood pathways. By modulating these receptors, buprenorphine may influence the symptoms of co-occurring mental health disorders. Some studies have suggested that buprenorphine can have positive effects on mood. As a result, that can provide a dual benefit in the treatment of both substance use and mental health disorders.

What Else Can Help in the Alcohol Withdrawal Process?

In addition to medication, integrating various support strategies can significantly assist individuals in navigating the complexities of the alcohol withdrawal process. These methods aim to address both the physical and psychological aspects of withdrawal, providing a comprehensive approach to recovery.

Medical Monitoring and Supervision

Monitoring and supervision of patients are important during the initial stages of alcohol withdrawal. In severe cases, withdrawal symptoms result in conditions such as delirium tremens. With a supervised medical setting, healthcare professionals can evaluate the severity of withdrawal symptoms, keep a close watch on vital signs, and provide immediate assistance if complications arise. This close monitoring helps provide a safe and controlled environment for individuals undergoing alcohol withdrawal.

Hydration and Nutritional Support

Alcohol withdrawal can result in dehydration and nutritional deficiencies because chronic alcohol use can hinder the body’s ability to absorb essential nutrients. Anyone undergoing this process will want to maintain hydration to counteract fluid loss from sweating and nausea. Intravenous fluids may be necessary in severe cases to address dehydration. Nutritional support, including vitamin supplements and a balanced diet, can help replenish essential nutrients and promote better health during withdrawal. 

Mental Health Interventions

Psychosocial treatments are also a vital component of the alcohol withdrawal process. Counseling, therapy, and support groups offer individuals a platform to address the emotional and psychological elements of their addiction. Cognitive behavioral therapy (CBT), motivational enhancement therapy (MET), and dialectical behavior therapy (DBT) are some evidence-based approaches that can help individuals develop coping strategies, manage stress, and overcome the challenges of recovery.

Support groups, such as Alcoholics Anonymous (AA) or SMART Recovery, provide a sense of community and shared experiences. Peer support can be beneficial during the withdrawal process. These groups give individuals encouragement, a place for understanding, and a sense of accountability.

Holistic Therapies

Holistic therapies are based on the belief that the mind, body, and spirit are interconnected. These treatment options focus on enhancing an individual’s overall well-being. During alcohol withdrawal, yoga, meditation, acupuncture, and mindfulness can be used alongside traditional treatment methods. They can help to reduce stress, improve mental clarity, and regulate emotions. These therapies provide individuals with valuable tools to help them face recovery challenges.

Exercise and Physical Activity

Maintaining a regular exercise routine and staying physically active can have significant benefits for individuals undergoing alcohol withdrawal. Exercise releases endorphins, which are neurotransmitters that promote feelings of well-being and help reduce stress levels.

Physical activity also helps regulate sleep patterns, alleviate anxiety, and improve overall mood. Incorporating exercise into an individual’s daily routine can be beneficial during this time. This health-promoting strategy supports individuals as they cope with the challenges of alcohol withdrawal.

Sleep Management

Many times, it is a common experience to suffer sleep problems during alcohol withdrawal. For this reason, individuals should focus on sleep health to maintain overall well-being. Creating a consistent sleep routine, optimizing the sleep environment, and avoiding stimulants before bedtime can help improve the quality of a person’s sleep. Sometimes, healthcare providers may recommend short-term sleep aids to help individuals manage insomnia.

Family and Social Support

The support of family and friends is invaluable during alcohol withdrawal. A strong support system can provide emotional encouragement and motivation for individuals navigating the challenges of withdrawal. Involving family members in recovery can also contribute to a healthier home environment. All that can help individuals be successful in their recovery journey.

Educational Programs and Coping Strategies

Educating individuals about addiction, the withdrawal process, and coping strategies can be very empowering. Psychoeducation provides a better understanding of the physiological and psychological aspects of alcohol withdrawal. It can help individuals make better decisions about their treatment. Providing coping strategies, stress management techniques, and relapse prevention skills enhances a person’s recovery process. 

Get Help for the Alcohol Withdrawal Process

Successfully overcoming alcohol withdrawal requires a personalized approach. By addressing the various elements of alcohol dependence, individuals can embark on a journey toward improved well-being and lasting recovery.

If you or someone you know is struggling with alcohol dependence, you will want to find a medical treatment program that meets your specific needs. At AlcoholAwareness.org, we offer the resources and support necessary to help you through this challenging time. Contact us to find out how we can assist you in this process.