Standard inpatient alcohol detox protocols guide you through five core phases: medical evaluation, acute withdrawal management, medication administration, continuous monitoring, and discharge planning. You’ll undergo risk stratification using tools like the CIWA-Ar scale, receive benzodiazepines through symptom-triggered or fixed-dose regimens, and get essential supplements including thiamine to prevent Wernicke’s encephalopathy. Understanding each phase’s clinical rationale helps you navigate what to expect throughout your treatment journey.
Core Phases of Standard Inpatient Alcohol Detox

Standard inpatient alcohol detox typically progresses through four core phases, each serving a distinct clinical purpose in safely managing withdrawal.
Inpatient alcohol detox follows four essential phases designed to guide you safely through withdrawal under medical supervision.
Phase 1: Evaluation and Medical Workup
You’ll undergo extensive assessment, including alcohol use history, baseline labs, and comorbid conditions identification. Clinicians initiate thiamine and nutritional support immediately.
Phase 2: Acute Withdrawal Management
You’re monitored intensively as symptoms emerge 6, 12 hours post-last drink. Seizure risk peaks at 24, 48 hours, while delirium tremens risk is highest at 48, 96 hours. Common symptoms during this phase include anxiety, irritability, insomnia, tremors, and nausea.
Phase 3: Medication Protocols
You’ll receive benzodiazepines as first-line therapy, titrated using CIWA-Ar scores. Adjunctive agents address residual symptoms. Oral medications like disulfiram, naltrexone, and acamprosate may also be considered as part of ongoing treatment planning.
Phase 4: Monitoring and Stabilization
You’re assessed for complications while psychiatric stabilization occurs. Relapse-prevention medications are considered once you’re medically stable and withdrawal resolves.
Admission Criteria and Risk Stratification
Before initiating the phased detox process, clinicians must determine whether inpatient care is appropriate through systematic admission criteria and risk stratification. You’ll undergo screening that evaluates your addiction history, biopsychosocial factors, and ASAM Dimensions 1-3, which assess withdrawal potential, biomedical conditions, and mental health status.
Risk stratification identifies factors warranting inpatient care: history of delirium tremens, withdrawal seizures, heavy alcohol use exceeding 12-15 drinks daily, or significant comorbidities. Age over 65, cognitive impairments, and inadequate social support networks also indicate higher-level care needs. Patients presenting with a CIWA score higher than 20 or experiencing hallucinations require immediate transfer to emergency department care.
Before admission, you’ll complete informed consent, acknowledging treatment protocols and expectations. Contraindications to outpatient detox, including severe mental health conditions, current seizure activity, or pregnancy, automatically qualify you for inpatient services. A physician reviews your addiction-focused history, and you’ll receive a physical examination within 24 hours. It’s important to understand that withdrawal management alone is not an effective treatment for alcohol use disorder and should be viewed as a component of initiating ongoing treatment.
Monitoring, Supportive Care, and Safety Measures

Once you’re admitted for inpatient alcohol detoxification, continuous monitoring becomes the cornerstone of safe withdrawal management. Your care team checks vital signs every four hours while you’re awake and one hour after each benzodiazepine dose. The monitoring frequency increases based on symptom severity and complication risk. Staff use the CIWA-Ar scale to evaluate withdrawal intensity, scoring you each shift when levels remain below 10.
Supportive care includes hydration, nutritional support, and electrolyte monitoring to prevent cardiac arrhythmias. You’ll receive daily evaluations examining mental status, sleep quality, mood, and suicidality for up to five days. Untreated or inadequately managed withdrawal can progress to generalized tonic-clonic seizures, delirium tremens, and potentially death, making thorough monitoring essential.
Safety protocols prioritize fall risk prevention through immediate provider notification when CIWA scores exceed 19 or when you require restraints. Staff alert physicians if benzodiazepine doses surpass established 24-hour thresholds.
Pharmacologic Management of Withdrawal
While monitoring and supportive care establish the foundation for safe withdrawal management, pharmacologic intervention addresses the underlying neurobiological disruption that drives alcohol withdrawal syndrome.
Pharmacologic treatment goes beyond symptom management, it directly targets the neurobiological chaos driving alcohol withdrawal syndrome.
Benzodiazepines as First-Line Treatment
You’ll find benzodiazepines recommended across all major guidelines, ASAM, NICE, WFSBP, and APA, due to their cross-tolerance with alcohol and proven efficacy in preventing seizures and delirium. For withdrawal symptom management, you’ll typically use diazepam for most patients or lorazepam when hepatic impairment exists.
Symptom-Triggered Protocols
Symptom-triggered dosing based on CIWA-Ar scores exceeding 8-10 points reduces total medication requirements considerably, averaging 100mg chlordiazepoxide versus 425mg with fixed schedules. This approach facilitates efficient medication de escalation while maintaining safety. CIWA-Ar assessments should continue every 4-8 hours until scores consistently remain below the medication threshold.
Adjunctive Therapies
You may add carbamazepine, gabapentin, or phenobarbital for moderate-to-severe cases requiring enhanced control beyond benzodiazepine monotherapy. These combination approaches are particularly important because severe withdrawal cases benefit from association with other drugs alongside first-line benzodiazepine treatment.
Vitamins, Labs, and Medical Complication Management

You should administer parenteral thiamine before any glucose-containing fluids to prevent precipitating Wernicke’s encephalopathy in thiamine-depleted patients. High-dose IV thiamine (200, 500 mg every 8 hours for 3, 5 days) is standard for high-risk individuals, followed by oral supplementation during recovery. Alongside thiamine protocols, you’ll need to obtain essential laboratory assessments including a detailed metabolic panel, magnesium, phosphorus, CBC with indices, folate, B12, and liver function tests to guide individualized management. Research indicates that vitamin C supplementation should also be considered alongside thiamine, as a significant portion of individuals with AUD admitted to ICU demonstrated severe deficiency. When managing magnesium replacement, you should target serum levels of 2.2-2.5 mg/dL and adjust dosing based on renal function throughout the detoxification process. Additionally, milk thistle supplementation may be considered as part of the protocol to help prevent further liver damage in patients with compromised hepatic function.
Thiamine Before Glucose Administration
Because chronic alcohol use depletes thiamine stores and impairs absorption by up to 50%, clinicians must administer thiamine before giving any IV glucose or carbohydrate load during alcohol detox. Proper thiamine timing prevents precipitation of Wernicke encephalopathy, since glucose metabolism rapidly consumes remaining thiamine reserves. Without this essential cofactor, pyruvate dehydrogenase and transketolase cannot function, causing energy failure in vulnerable brain regions.
Optimal thiamine dosing depends on risk stratification. For patients without clear Wernicke signs, you’ll give 300 mg orally daily for three to five days. High-risk patients with malnutrition, liver disease, or neurologic symptoms require 200-500 mg IV two to three times daily for at least three days. Studies show patients receiving at least three days of thiamine treatment experienced symptom resolution. Always supplement magnesium, as deficiency impairs thiamine utilization. Intramuscular thiamine injection may be unsafe in these patients due to alcohol-associated thrombocytopenia and coagulopathy. This protocol represents standard of care in preventing irreversible neurologic damage. Autopsy studies reveal that Wernicke encephalopathy remains significantly underdiagnosed, with only 5% of cases identified before death, underscoring the critical importance of empiric treatment in at-risk patients.
Essential Laboratory Assessments
Although thiamine administration establishes the foundation for neuroprotection, thorough laboratory assessment determines the full scope of medical complications requiring management during alcohol detox. You’ll need to order an all-encompassing metabolic profile, CBC with differential, and liver function tests to evaluate hepatic impairment, renal function, and bone marrow suppression. The AST:ALT ratio of 2:1 or higher suggests alcohol-related liver damage.
Electrolyte derangements require close monitoring since severe disturbances risk cardiac arrhythmias. You should include magnesium and phosphorus levels for replacement protocols. Urine toxicology screens identify polysubstance use that may complicate withdrawal management. Folic acid supplementation should accompany thiamine to prevent megaloblastic anemia in alcohol-dependent patients.
Regarding biomarker utility, phosphatidylethanol and ethyl glucuronide prove unreliable for acute withdrawal assessment. Instead, blood alcohol levels detect recent consumption. Screen high-risk patients for hepatitis, HIV, and tuberculosis. Obtain an ECG to assess QTc interval before initiating certain pharmacotherapies. Early identification of complications through comprehensive laboratory assessment is crucial since alcohol withdrawal delirium carries a mortality rate ranging from 1-15%.
Protocol Models and Discharge Planning
Most inpatient alcohol detoxification programs rely on one of three protocol models: symptom-triggered, fixed-dose, or multimodal hybrid approaches. Symptom-triggered protocols use validated tools like CIWA-Ar to administer benzodiazepines only when scores exceed 8, reducing total medication exposure. Fixed-dose regimens deliver scheduled tapering doses, providing additional medication based on symptom severity. Multimodal approaches combine front-loading with symptom monitoring, incorporating pharmacologic alternatives like phenobarbital when needed. Fixed-interval dosing remains particularly useful when frequent monitoring is not feasible due to staffing or patient reliability concerns.
Comprehensive discharge planning begins once withdrawal symptoms fully resolve. You shouldn’t prescribe PRN medications for post-discharge symptom management due to rebound risks. Guarantee patients receive nutritional support, thiamine supplementation, and follow-up appointments before leaving. Consider extended inpatient care for individuals with seizure history, prior severe withdrawal, or inadequate social support networks to prevent complications.
Frequently Asked Questions
How Long Does a Typical Inpatient Alcohol Detox Stay Last?
You’ll typically spend 5-7 days in inpatient alcohol detox, though your stay may extend to 10 days for severe cases. The alcohol detox duration depends on your withdrawal severity, consumption history, and co-occurring conditions. In this detox timeline overview, you’ll experience peak symptoms between 24-72 hours after your last drink. Medical staff will monitor you continuously, administering medications as needed to guarantee safe stabilization before you move to ongoing treatment.
Can Family Members Visit During Inpatient Alcohol Detoxification?
During the initial detox phase, you typically can’t receive family visits. Most facilities enforce strict visitation policies that restrict contact for the first 3-7 days while you’re experiencing active withdrawal symptoms. Staff need uninterrupted private room access to monitor your essential signs and manage symptoms effectively. After you’ve stabilized and completed detox, you’ll regain visiting privileges with scheduled appointments, therapist approval, and designated meeting areas to support your recovery process.
What Is the Average Cost of Inpatient Alcohol Detox Programs?
You’ll typically pay between $6,000 and $20,000 for a standard 30-day inpatient alcohol detox program, with average program costs varying based on location, amenities, and clinical intensity. Medical detox alone runs approximately $250, $800 daily. Your insurance coverage options can greatly/considerably/substantially reduce out-of-pocket expenses, many plans cover up to 80% of treatment costs. You should verify benefits directly with your provider before admission to understand your financial responsibility.
Will I Experience Pain During the Alcohol Detoxification Process?
You’ll likely experience some discomfort during alcohol detox, though it varies based on your drinking history. Common withdrawal symptoms include headaches, nausea, tremors, anxiety, and muscle tension rather than sharp, localized pain. Under medical supervision, clinicians use evidence-based protocols, typically benzodiazepines, to minimize discomfort and prevent dangerous complications like seizures. Symptoms typically peak within 24, 72 hours, then gradually subside. Inpatient settings provide round-the-clock monitoring to manage your symptoms effectively throughout the process.
Can I Bring Personal Items Like Phones During Inpatient Detox?
Most inpatient detox programs restrict or prohibit smartphones and internet-enabled devices. You’ll encounter strict electronic device policies designed to minimize distractions, protect patient confidentiality, and prevent contact with triggering influences during your vulnerable early recovery period. Staff typically inventory your belongings upon admission, and personal belongings storage is provided for restricted items. You can usually bring approved essentials, clothing, toiletries, and reading materials. Check your facility’s specific packing list before arrival for exact guidelines.
