Does Disulfiram Help with Alcohol Withdrawal?

Robert Gerchalk

Robert is our health care professional reviewer of this website. He worked for many years in mental health and substance abuse facilities in Florida, as well as in home health (medical and psychiatric), and took care of people with medical and addictions problems at The Johns Hopkins Hospital in Baltimore. He has a nursing and business/technology degrees from The Johns Hopkins University.

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Why Is Disulfiram Used To Treat Alcoholism?

When trying to overcome alcoholism, many people encounter the unpleasant and difficult process of alcohol withdrawal. Disulfiram is one of many drugs that have recently come to light as a potential means of alleviating withdrawal symptoms. In this article, we’ll look at how disulfiram works during alcohol withdrawal, what advantages it may have and how it fits into the bigger picture of addiction therapy.

What Is Disulfiram?

Antabuse, the commercial name for disulfiram, is a medicine that works in a very specific way. It prevents alcohol consumption by blocking the enzyme aldehyde dehydrogenase, an essential enzyme in the breakdown of acetaldehyde. Ingesting disulfiram causes the buildup of acetaldehyde in the body, which, in turn, causes the unpleasant side effects associated with alcohol use. When employed in the therapy of alcohol use disorder, this unpleasant response acts as a deterrent, preventing people from drinking and encouraging sobriety.

What to Expect During Alcohol Withdrawal

Before delving into the role of disulfiram in alcohol withdrawal, it’s essential to understand the typical symptoms that individuals may experience during this challenging phase of recovery. As the body readjusts to life without alcohol, a series of complicated symptoms, known as alcohol withdrawal, begins. Some variables that affect how bad withdrawal symptoms will be include how long and heavy of an alcohol user you are, how healthy you are in general and how your metabolism works.

Headaches

Because abrupt abstinence triggers complex neurobiological changes, headaches are a frequent withdrawal symptom following alcohol cessation. Brain blood flow and neurotransmitter levels are both affected by long-term alcohol use. If one suddenly stops drinking, these adjustments become upset, and a rebound effect ensues. Neurotransmitter imbalances, enlarged blood vessels and increased sensitivity to stimuli all play a role in the development of headaches. This unease is the brain’s way of trying to readjust itself after consuming alcohol, which has a depressive impact. With the right amount of water, food and social support, you can lessen the severity of headaches caused by alcohol withdrawal.

Intense Cravings

There are psychological and physiological components that contribute to the intense cravings that characterize alcohol withdrawal. Drinking alcohol regularly messes with your brain’s reward system, so you start to want it more and more. Because of its habitual pleasurable effects, alcohol causes the brain to exhibit intense cravings for its reintroduction during withdrawal. When there is an imbalance in neurotransmitters, especially serotonin and dopamine, the cravings become much worse. Overcoming these cravings usually requires a multipronged approach that takes into account the psychological and neurological components of addiction in addition to counseling and behavioral therapies.

Muscle Aches and Cramps

The body’s adaptation to life without alcohol sometimes manifests as pain and cramps in the muscles. Prolonged alcohol use disrupts the central nervous system via neurotransmitter dysfunctions, which, in turn, generate a variety of adverse effects, including musculoskeletal anxiety. Muscle pains get worse during withdrawal because of changes in neurotransmitter levels and electrolyte abnormalities. Also, people with an alcohol use disorder often experience dehydration, which may make their muscular cramps worse. You can find relief from these symptoms during the alcohol withdrawal period by staying hydrated, doing some modest physical exercise and treating dietary shortages.

Gastrointestinal Issues

The severe effects of long-term alcohol use on the digestive tract make gastrointestinal problems common during alcohol withdrawal. When you suddenly stop drinking, your stomach and intestines have to adapt to the new normal. A variety of changes occur as a result of these alterations, including in the gut flora, the motility of the gut and acid production. Nausea, vomiting and diarrhea are common side effects that people commonly experience. Managing the gastrointestinal pain associated with alcohol withdrawal requires a combination of supportive measures, enough hydration and nutritional assistance to help restore digestive homeostasis.

Fatigue and Sleep Problems

Withdrawal symptoms, such as sleep disturbances and extreme fatigue, are common among those overcoming alcoholism. Insomnia during withdrawal is a symptom of sleep pattern and neurotransmitter disruption, which is caused by chronic alcohol usage. When you regularly use alcohol, your body becomes used to its calming effects and has difficulty regulating sleep when you don’t. When you cut down on alcohol, your body has to acclimate to not having any stimulating effects, which may lead to fatigue. When taken as a whole, these symptoms highlight the complex neurobiological changes that take place during withdrawal. During recuperation, it is essential to establish regular sleep schedules, take care of nutritional requirements and create a healthy sleep environment to reduce weariness and sleep disruptions.

How Does Disulfiram Help Alcoholism?

Disulfiram plays a distinctive role in supporting individuals on their path to recovery. When taken following a provider’s instructions, this medicine can be the difference between achieving long-term sobriety and relapsing. 

Deterrent Effect

When used to treat alcoholism, disulfiram acts as a strong deterrent. It causes acetaldehyde to accumulate in the body in response to alcohol use by blocking aldehyde dehydrogenase. A severe dislike for alcohol develops as a consequence of the accumulation of negative symptoms, including nausea, headaches and flushes. The association of drinking with immediate and painful effects strengthens the commitment to sobriety, thanks to the deterrent impact.

Behavioral Conditioning

Disulfiram is essential in behavioral conditioning in addition to its pharmacological effects. People taking the medicine for the first time learn to associate drinking with bad things happening to them. The unpleasant side effects caused by disulfiram work as a barrier, influencing behaviors and encouraging a way of thinking that promotes sobriety in the long run.

Maintaining Abstinence

While it doesn’t solve the problem of alcoholism at its source, disulfiram does help people stay sober by acting as a constant reminder to not drink. It works exceptionally well at helping people achieve the primary objective of staying sober and avoiding harmful drinking habits.

Psychological Support

Having someone to lean on emotionally and mentally is crucial while fighting alcoholism. Disulfiram gives this help by making it more difficult to drink. As a psychological defense mechanism, the dread of its unpleasant side effects strengthens one’s will to overcome the obstacles on the road to recovery. This assistance goes beyond only alleviating the physical symptoms of alcoholism; it also deals with the many mental challenges that many people face.

Structured Treatment Plans

Incorporating disulfiram into alcoholism treatment strategies improves the effectiveness of therapies as a whole. Within the larger framework of therapeutic modalities, it plays a special function, offering a one-of-a-kind and practical resource for clients and medical practitioners alike. The organized format of these treatment programs guarantees a holistic strategy, addressing all aspects of alcoholism.

Long-Lasting Impact

Disulfiram has a long-term effect on recovery when included in treatment plans. The unpleasant side effects of the medicine help people stay sober for longer, which improves their chances of avoiding relapse and fostering long-term recovery.

Getting Treatment for Alcoholism

Quitting drinking is a brave and life-altering decision that leads to better health and greater happiness. Seeking treatment is not only a declaration of personal commitment but also an acknowledgment of the complexities surrounding alcohol dependence. All three of your treatment options — residential programs, outpatient therapy and continuing aftercare service — offer their own set of advantages.

Residential Programs

One way to treat alcoholism is through a residential or inpatient program. These types provide a more regulated and all-encompassing environment. Those in need of intense care, a nurturing atmosphere and respite from outside stresses greatly benefit from residential treatment. 

Constant supervision and assistance are major perks of residential programs. People in residential care have round-the-clock access to doctors, therapists and support workers. This allows for a thorough and rapid response to any new problems that may arise.

A supervised detoxification period is a common first step in residential treatment programs. As people go through withdrawal, medical experts keep a careful eye on them to make sure they’re safe and give them medicine, such as benzodiazepines, to help with the symptoms. Prior to beginning therapeutic measures, it is essential to stabilize people physiologically.

To facilitate therapeutic treatments, residential programs provide a structured setting. The daily regimen incorporates a variety of methods, such as holistic techniques, group therapy and individual counseling. Individuals can build coping mechanisms and get to the root of their alcohol use problems because of the intensive nature of these programs.

Outpatient Treatment

You can get the care you need without having to drastically alter your everyday routines, thanks to outpatient therapy. Outpatient treatment works well for those with less severe alcoholism as well as those who have obligations they need to attend to while also receiving treatment. 

Outpatient therapy entails a lesser degree of care in comparison to residential programs. There is less emphasis on total immersion, but people still gain from therapeutic treatments, medical supervision and counseling. People who do not need round-the-clock monitoring or extensive therapeutic treatments may benefit from outpatient therapy because of this.

The goal of outpatient therapy is to help patients incorporate their new coping mechanisms into their regular routines. The ability to immediately put into practice what one learns in treatment makes the transition from therapy to a normal life much easier. 

To meet the wide range of demands experienced by those participating in outpatient therapy, every person receives a tailored treatment plan. Individualized treatment plans, which usually include counseling, education and therapy, allow clients to achieve unique objectives. This one-of-a-kind method guarantees that people get the help that is most applicable to their specific situation.

Even though outpatient therapy gives clients greater freedom, they are nevertheless held accountable to a certain degree. Group meetings, therapy sessions and check-ins at regular intervals provide a steady framework of support that helps people stay on track and get the constructive feedback they need to stay sober.

Ongoing Aftercare Services

Ongoing aftercare services encompass continue therapeutic support. This may involve individual counseling, group therapy or specialized therapeutic modalities to address specific issues or challenges that arise during the recovery journey. Aftercare often includes making use of community services and joining support groups. People benefit from the shared experiences and support networks formed during therapy even after treatment ends, whether it’s via 12-step programs, SMART Recovery or other community-based efforts.

The availability of crisis intervention services is another component of ongoing aftercare programs. Should individuals face unexpected challenges or relapse, having a structured plan in place to provide immediate support can help them navigate through crises and regain stability in their recovery.

Are you interested in learning how you can use disulfiram for alcohol withdrawal? Alcohol Awareness helps people just like you every day connect with treatment providers in their area. We understand how addictions to drugs and alcohol can absolutely wreak havoc on a person’s life. That’s why we do everything we can to get people sober, one client at a time.